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Index > Protein center > MYLK(Gene name) > Human
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  • MYLK (Gene name),
  • Myosin light chain kinase, smooth muscle (Protein name ),  MYLK_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    MYLK(MLCK;MLCK1;MYLK1);
    Protein name:
    Myosin light chain kinase, smooth muscle(MLCK);
    Alternative:
    Telokin;Kinase-related protein(KRP);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    All isoforms including Telokin bind calmodulin. Interacts with SVIL.
    Function:
    Calcium/calmodulin-dependent enzyme implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activty (By similarity). Implicated in the regulation of endothelial as well as vascular permeability. In the nervous system it has been shown to control the growth initiation of astrocytic processes in culture and to participate in transmitter release at synapses formed between cultured sympathetic ganglion cells. Critical participant in signaling sequences that result in fibroblast apoptosis.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    1914
    Sequence:
    50:
    MGDVKLVASS | HISKTSLSVD | PSRVDSMPLT | EAPAFILPPR | NLCIKEGATA | 
    100:
    KFEGRVRGYP | EPQVTWHRNG | QPITSGGRFL | LDCGIRGTFS | LVIHAVHEED | 
    150:
    RGKYTCEATN | GSGARQVTVE | LTVEGSFAKQ | LGQPVVSKTL | GDRFSAPAVE | 
    200:
    TRPSIWGECP | PKFATKLGRV | VVKEGQMGRF | SCKITGRPQP | QVTWLKGNVP | 
    250:
    LQPSARVSVS | EKNGMQVLEI | HGVNQDDVGV | YTCLVVNGSG | KASMSAELSI | 
    300:
    QGLDSANRSF | VRETKATNSD | VRKEVTNVIS | KESKLDSLEA | AAKSKNCSSP | 
    350:
    QRGGSPPWAA | NSQPQPPRES | KLESCKDSPR | TAPQTPVLQK | TSSSITLQAA | 
    400:
    RVQPEPRAPG | LGVLSPSGEE | RKRPAPPRPA | TFPTRQPGLG | SQDVVSKAAN | 
    450:
    RRIPMEGQRD | SAFPKFESKP | QSQEVKENQT | VKFRCEVSGI | PKPEVAWFLE | 
    500:
    GTPVRRQEGS | IEVYEDAGSH | YLCLLKARTR | DSGTYSCTAS | NAQGQLSCSW | 
    550:
    TLQVERLAVM | EVAPSFSSVL | KDCAVIEGQD | FVLQCSVRGT | PVPRITWLLN | 
    600:
    GQPIQYARST | CEAGVAELHI | QDALPEDHGT | YTCLAENALG | QVSCSAWVTV | 
    650:
    HEKKSSRKSE | YLLPVAPSKP | TAPIFLQGLS | DLKVMDGSQV | TMTVQVSGNP | 
    700:
    PPEVIWLHNG | NEIQESEDFH | FEQRGTQHSL | CIQEVFPEDT | GTYTCEAWNS | 
    750:
    AGEVRTQAVL | TVQEPHDGTQ | PWFISKPRSV | TASLGQSVLI | SCAIAGDPFP | 
    800:
    TVHWLRDGKA | LCKDTGHFEV | LQNEDVFTLV | LKKVQPWHAG | QYEILLKNRV | 
    850:
    GECSCQVSLM | LQNSSARALP | RGREPASCED | LCGGGVGADG | GGSDRYGSLR | 
    900:
    PGWPARGQGW | LEEEDGEDVR | GVLKRRVETR | QHTEEAIRQQ | EVEQLDFRDL | 
    950:
    LGKKVSTKTL | SEDDLKEIPA | EQMDFRANLQ | RQVKPKTVSE | EERKVHSPQQ | 
    1000:
    VDFRSVLAKK | GTSKTPVPEK | VPPPKPATPD | FRSVLGGKKK | LPAENGSSSA | 
    1050:
    ETLNAKAVES | SKPLSNAQPS | GPLKPVGNAK | PAETLKPMGN | AKPAETLKPM | 
    1100:
    GNAKPDENLK | SASKEELKKD | VKNDVNCKRG | HAGTTDNEKR | SESQGTAPAF | 
    1150:
    KQKLQDVHVA | EGKKLLLQCQ | VSSDPPATII | WTLNGKTLKT | TKFIILSQEG | 
    1200:
    SLCSVSIEKA | LPEDRGLYKC | VAKNDAGQAE | CSCQVTVDDA | PASENTKAPE | 
    1250:
    MKSRRPKSSL | PPVLGTESDA | TVKKKPAPKT | PPKAAMPPQI | IQFPEDQKVR | 
    1300:
    AGESVELFGK | VTGTQPITCT | WMKFRKQIQE | SEHMKVENSE | NGSKLTILAA | 
    1350:
    RQEHCGCYTL | LVENKLGSRQ | AQVNLTVVDK | PDPPAGTPCA | SDIRSSSLTL | 
    1400:
    SWYGSSYDGG | SAVQSYSIEI | WDSANKTWKE | LATCRSTSFN | VQDLLPDHEY | 
    1450:
    KFRVRAINVY | GTSEPSQESE | LTTVGEKPEE | PKDEVEVSDD | DEKEPEVDYR | 
    1500:
    TVTINTEQKV | SDFYDIEERL | GSGKFGQVFR | LVEKKTRKVW | AGKFFKAYSA | 
    1550:
    KEKENIRQEI | SIMNCLHHPK | LVQCVDAFEE | KANIVMVLEI | VSGGELFERI | 
    1600:
    IDEDFELTER | ECIKYMRQIS | EGVEYIHKQG | IVHLDLKPEN | IMCVNKTGTR | 
    1650:
    IKLIDFGLAR | RLENAGSLKV | LFGTPEFVAP | EVINYEPIGY | ATDMWSIGVI | 
    1700:
    CYILVSGLSP | FMGDNDNETL | ANVTSATWDF | DDEAFDEISD | DAKDFISNLL | 
    1750:
    KKDMKNRLDC | TQCLQHPWLM | KDTKNMEAKK | LSKDRMKKYM | ARRKWQKTGN | 
    1800:
    AVRAIGRLSS | MAMISGLSGR | KSSTGSPTSP | LNAEKLESEE | DVSQAFLEAV | 
    1850:
    AEEKPHVKPY | FSKTIRDLEV | VEGSAARFDC | KIEGYPDPEV | VWFKDDQSIR | 
    1900:
    ESRHFQIDYD | EDGNCSLIIS | DVCGDDDAKY | TCKAVNSLGE | ATCTAELIVE | 
    1914:
    TMEEGEGEGE | EEEE
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    KEGG:
    SMR:
    MIM:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human MLCK
    Cat.:
    E1106h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human MLCK
    MSDS:
    Please sign in first.
    ELISA Kit for Human MLCK
    Cat.:
    E1106b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human MLCK
    MSDS:
    Please sign in first.
    ELISA Kit for Human MLCK
    Cat.:
    E1106c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human MLCK
    Cat.:
    E1106m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human MLCK
    Cat.:
    U1106m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human MLCK
    Cat.:
    U1106c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human MLCK
    Cat.:
    U1106b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human MLCK
    MSDS:
    Please sign in first.
    CLIA Kit for Human MLCK
    MSDS:
    Please sign in first.
    CLIA Kit for Human MLCK
    Cat.:
    U1106h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human MLCK
    Cat.:
    P1106Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human MLCK
    Polyclonal Antibody for Human MLCK
    Polyclonal Antibody for Human MLCK
    Cat.:
    P1106Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human MLCK
    Polyclonal Antibody for Human MLCK
    Monoclonal Antibody for Human MLCK
    Monoclonal Antibody for Human MLCK
    Monoclonal Antibody for Human MLCK
    Monoclonal Antibody for Human MLCK
    Monoclonal Antibody for Human MLCK
    Monoclonal Antibody for Human MLCK
    Protein for Human MLCK
    Protein for Human MLCK
    Protein for Human MLCK
    Protein for Human MLCK
    Protein for Human MLCK
    Protein for Human MLCK

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The human myosin light chain kinase (MLCK) from hippocampus: cloning, sequencing, expression, and localization to 3qcen-q21."
      Potier M.-C. , Chelot E. , Pekarsky Y. , Gardiner K. , Rossier J. , Turnell W.G.
      Genomics29:562-570(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 9);TISSUE SPECIFICITY
      tissue: Hippocampus.
    2. 2.
      "Myosin light chain kinase in endothelium: molecular cloning and regulation."
      Garcia J.G.N. , Lazar V.L. , Gilbert-Mcclain L.I. , Gallagher P.J. , Verin A.D.
      Am. J. Respir. Cell Mol. Biol.16:489-494(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Umbilical vein endothelial cell.
    3. 3.
      "A single human myosin light chain kinase gene (MLCK; MYLK)."
      Lazar V.L. , Garcia J.G.N.
      Genomics57:256-267(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2; 3A AND 3B);NUCLEOTIDE SEQUENCE [MRNA] OF 1281-1914 (ISOFORM 4)
      tissue: Umbilical vein.
    4. 4.
      "Differential regulation of alternatively spliced endothelial cell myosin light chain kinase isoforms by p60(Src)."
      Birukov K.G. , Csortos C. , Marzilli L. , Dudek S. , Ma S.-F. , Bresnick A.R. , Verin A.D. , Cotter R.J. , Garcia J.G.N.
      J. Biol. Chem.276:8567-8573(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION (ISOFORMS 1 AND 2);PROTEIN SEQUENCE OF 457-476 AND 968-985;FUNCTION;BIOPHYSICOCHEMICAL PROPERTIES;PHOSPHORYLATION AT TYR-464 AND TYR-471;CALMODULIN-BINDING;ENZYME REGULATION
    5. 5.
      "Analysis of the kinase-related protein gene found at human chromosome 3q21 in a multi-gene cluster: organization, expression, alternative splicing and polymorphic marker."
      Watterson D.M. , Schavocky J.P. , Guo L. , Weiss C. , Chlenski A. , Shrinsky V.P. , Van Eldik L.J. , Haiech J.
      J. Cell. Biochem.75:481-491(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 6);NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 8);NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1614-1914 (ISOFORM 9/DEL-1790);TISSUE SPECIFICITY
      tissue: Lung.
      tissue: Placenta.
    6. 6.
      "A differentiation-dependent splice variant of myosin light chain kinase, MLCK1, regulates epithelial tight junction permeability."
      Clayburgh D.R. , Rosen S. , Witkowski E.D. , Wang F. , Blair S. , Dudek S. , Garcia J.G. , Alverdy J.C. , Turner J.R.
      J. Biol. Chem.279:55506-55513(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
      tissue: Intestinal epithelium.
    7. 7.
      "The N-terminus of the long MLCK induces a disruption in normal spindle morphology and metaphase arrest."
      Dulyaninova N.G. , Patskovsky Y.V. , Bresnick A.R.
      J. Cell Sci.117:1481-1493(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION IN CELL CYCLE;SUBCELLULAR LOCATION
      tissue: Cervix carcinoma.
    8. 8.
      "HeLa myosin light chain kinase."
      Kikuchi A. , Murata-Hori M. , Hosoya H.
      Submitted (2000-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 5)
      tissue: Cervix carcinoma.
    9. 9.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 6; 7 AND 8)
      tissue: Testis.
    10. 10.
      "The DNA sequence, annotation and analysis of human chromosome 3."
      Muzny D.M. , Scherer S.E. , Kaul R. , Wang J. , Yu J. , Sudbrak R. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , more...
      Nature440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    12. 12.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 6 AND 8)
    13. 13.
      Watterson D.M.
      Submitted (1995-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1456-1914 (ISOFORM 9/DEL-1790)
      tissue: Placenta.
    14. 14.
      "Novel interaction of cortactin with endothelial cell myosin light chain kinase."
      Dudek S.M. , Birukov K.G. , Zhan X. , Garcia J.G.N.
      Biochem. Biophys. Res. Commun.298:511-519(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CTTN;PHOSPHORYLATION AT TYR-464 AND TYR-471 BY SRC
    15. 15.
      "Myosin light chain kinase modulates hypotonicity-induced Ca2+ entry and Cl- channel activity in human cervical cancer cells."
      Shen M.-R. , Furla P. , Chou C.-Y. , Ellory J.C.
      Pflugers Arch.444:276-285(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN HYPOTONICITY RESPONSE;ENZYME REGULATION
    16. 16.
      "Quantitative measurements of Ca(2+)/calmodulin binding and activation of myosin light chain kinase in cells."
      Geguchadze R. , Zhi G. , Lau K.S. , Isotani E. , Persechini A. , Kamm K.E. , Stull J.T.
      FEBS Lett.557:121-124(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION BY CALCIUM
    17. 17.
      "Distinct temporal-spatial roles for rho kinase and myosin light chain kinase in epithelial purse-string wound closure."
      Russo J.M. , Florian P. , Shen L. , Graham W.V. , Tretiakova M.S. , Gitter A.H. , Mrsny R.J. , Turner J.R.
      Gastroenterology128:987-1001(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN WOUND HEALING
    18. 18.
      "Tumor necrosis factor-induced long myosin light chain kinase transcription is regulated by differentiation-dependent signaling events. Characterization of the human long myosin light chain kinase promoter."
      Graham W.V. , Wang F. , Clayburgh D.R. , Cheng J.X. , Yoon B. , Wang Y. , Lin A. , Turner J.R.
      J. Biol. Chem.281:26205-26215(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION BY TNF;TISSUE SPECIFICITY
    19. 19.
      "Myosin light chain kinase plays a role in the regulation of epithelial cell survival."
      Connell L.E. , Helfman D.M.
      J. Cell Sci.119:2269-2281(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN EPITHELIAL CELL SURVIVAL;ENZYME REGULATION
    20. 20.
      "Ca2+-calmodulin-dependent myosin light chain kinase is essential for activation of TRPC5 channels expressed in HEK293 cells."
      Shimizu S. , Yoshida T. , Wakamori M. , Ishii M. , Okada T. , Takahashi M. , Seto M. , Sakurada K. , Kiuchi Y. , Mori Y.
      J. Physiol. (Lond.)570:219-235(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN TRPC5 REGULATION;ENZYME REGULATION
    21. 21.
      "Myosin light-chain kinase contributes to the proliferation and migration of breast cancer cells through cross-talk with activated ERK1/2."
      Zhou X. , Liu Y. , You J. , Zhang H. , Zhang X. , Ye L.
      Cancer Lett.270:312-327(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN CELL MIGRATION
    22. 22.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1438;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Platelet.
    23. 23.
      "Nonmuscle myosin light-chain kinase mediates neutrophil transmigration in sepsis-induced lung inflammation by activating beta2 integrins."
      Xu J. , Gao X.-P. , Ramchandran R. , Zhao Y.-Y. , Vogel S.M. , Malik A.B.
      Nat. Immunol.9:880-886(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS PTK2B/PYK2 KINASE;INTERACTION WITH PTK2B/PYK2
    24. 24.
      "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."
      Han G. , Ye M. , Zhou H. , Jiang X. , Feng S. , Jiang X. , Tian R. , Wan D. , Zou H. , Gu J.
      Proteomics8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1438;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    25. 25.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    26. 26.
      "Androgens down-regulate myosin light chain kinase in human prostate cancer cells."
      Leveille N. , Fournier A. , Labrie C.
      J. Steroid Biochem. Mol. Biol.114:174-179(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION BY ANDROGENS
    27. 27.
      "Arrest defective-1 controls tumor cell behavior by acetylating myosin light chain kinase."
      Shin D.H. , Chun Y.-S. , Lee K.-H. , Shin H.-W. , Park J.-W.
      PLoS ONE4:E7451-E7451(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN TUMOR CELL MIGRATION;ACETYLATION AT LYS-608 BY NAA10/ARD1;INTERACTION WITH NAA10/ARD1;MUTAGENESIS OF LYS-608
    28. 28.
      "Myosin light chain kinase is responsible for high proliferative ability of breast cancer cells via anti-apoptosis involving p38 pathway."
      Cui W.-J. , Liu Y. , Zhou X.-L. , Wang F.-Z. , Zhang X.-D. , Ye L.-H.
      Acta Pharmacol. Sin.31:725-732(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN BREAST CANCER
    29. 29.
      "Modulation of factors affecting optic nerve head astrocyte migration."
      Miao H. , Crabb A.W. , Hernandez M.R. , Lukas T.J.
      Invest. Ophthalmol. Vis. Sci.51:4096-4103(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN OPTIC NERVE HEAD ASTROCYTE MIGRATION
    30. 30.
      "Quantitative distribution and colocalization of non-muscle myosin light chain kinase isoforms and cortactin in human lung endothelium."
      Brown M. , Adyshev D. , Bindokas V. , Moitra J. , Garcia J.G.N. , Dudek S.M.
      Microvasc. Res.80:75-88(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;INTERACTION WITH CTTN;SUBCELLULAR LOCATION
    31. 31.
      "Abl tyrosine kinase phosphorylates nonmuscle Myosin light chain kinase to regulate endothelial barrier function."
      Dudek S.M. , Chiang E.T. , Camp S.M. , Guo Y. , Zhao J. , Brown M.E. , Singleton P.A. , Wang L. , Desai A. , Arce F.T. , Lal R. , Van Eyk J.E. , Imam S.Z. , Garcia J.G.N.
      Mol. Biol. Cell21:4042-4056(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-231; TYR-464; TYR-556; TYR-611; TYR-792; TYR-846; TYR-1449; TYR-1575 AND TYR-1635 BY ABL1;INTERACTION WITH CTTN AND ABL1
    32. 32.
      "The angiotensin II type 1 receptor induces membrane blebbing by coupling to Rho A, Rho kinase, and myosin light chain kinase."
      Godin C.M. , Ferguson S.S.G.
      Mol. Pharmacol.77:903-911(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN MEMBRANE BLEBBING
    33. 33.
      "Non-muscle myosin light chain kinase isoform is a viable molecular target in acute inflammatory lung injury."
      Mirzapoiazova T. , Moitra J. , Moreno-Vinasco L. , Sammani S. , Turner J.R. , Chiang E.T. , Evenoski C. , Wang T. , Singleton P.A. , Huang Y. , Lussier Y.A. , Watterson D.M. , Dudek S.M. , Garcia J.G.N.
      Am. J. Respir. Cell Mol. Biol.44:40-52(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN INFLAMMATORY RESPONSE
    34. 34.
      "Organometallic pyridylnaphthalimide complexes as protein kinase inhibitors."
      Blanck S. , Cruchter T. , Vultur A. , Riedel R. , Harms K. , Herlyn M. , Meggers E.
      Organometallics30:4598-4606(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION
    35. 35.
      "Myosin, transgelin, and myosin light chain kinase: expression and function in asthma."
      Leguillette R. , Laviolette M. , Bergeron C. , Zitouni N. , Kogut P. , Solway J. , Kachmar L. , Hamid Q. , Lauzon A.-M.
      Am. J. Respir. Crit. Care Med.179:194-204(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON ASTHMA;INDUCTION BY ASTHMA
    36. 36.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    37. 37.
      "Solution structure of the eighth Ig-like domain of human myosin light chain kinase."
      RIKEN structural genomics initiative (RSGI)
      Submitted (2005-11) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1238-1338
    38. 38.
      "A coupled equilibrium shift mechanism in calmodulin-mediated signal transduction."
      Gsponer J. , Christodoulou J. , Cavalli A. , Bui J.M. , Richter B. , Dobson C.M. , Vendruscolo M.
      Structure16:736-746(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1742-1760 IN COMPLEX WITH CALMODULIN
    39. 39.
      "Patterns of somatic mutation in human cancer genomes."
      Greenman C. , Stephens P. , Smith R. , Dalgliesh G.L. , Hunter C. , Bignell G. , Davies H. , Teague J. , Butler A. , Stevens C. , Edkins S. , O'Meara S. , Vastrik I. , Schmidt E.E. , Avis T. , Barthorpe S. , Bhamra G. , Buck G. , more...
      Nature446:153-158(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] ALA-261; ALA-276; HIS-378; VAL-405; SER-443; GLY-607; ALA-652; CYS-656; MET-692; THR-701; MET-709; VAL-1527 AND LEU-1588
    40. 40.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AAT7 PRO-1759;VARIANTS VAL-128; HIS-133; ARG-160; CYS-656; ALA-1085; MET-1213; LYS-1399 AND THR-1754;CHARACTERIZATION OF VARIANT AAT7 PRO-1759;CHARACTERIZATION OF VARIANT THR-1754
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